Those are three questions. I need them to be answered

 

Those are three questions. I need them to be answered carefully each question has many concept please go through them in details. I need them in 6 pages with references from pubmed and other official resources. the last time I got bad grade because of missing some answers from the details questions, the answers were not completed . please, answer them carefully each question contains other specific questions. Thank you.

Requirements: 6 pages 

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