Describe the operation of gas-chromatograph mass spectrometry

Please answer two questions from section A and two questions from section

B: Section A 1. Describe the sample preparation procedures before injection into a gas chromatograph column (500 words max + figures if required; 12.5 marks). 2. Describe the operation of gas-chromatograph mass spectrometry. (500 words max + figures if required; 12.5 marks) 3. Describe the applications of metabolomics (500 words max + figures/models if required; 12.5 marks).

Section B

1. Describe the application of targeted proteomics and it use of SRM mass spectrometry. (500 words max + figures/models if required; 12.5 marks). 2. Describe the operation of a triple quad (QqQ) mass spectrometer in SRM mode (500 words max + figures/models if required; 12.5 marks). 3. Discuss the advantages and disadvantages of targeted vs. discovery proteomics. (500 words max + figures/models if required; 12.5 marks)

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