Efficacy of Folic Acid Therapy in Preventing Stroke Report Nursing Assignment Help

Provide a report on the Efficacy of Folic Acid Therapy in Primary Prevention of Stroke among Adults with Hypertension in China.

Expert Solution Preview

Introduction:
In recent years, stroke has become a leading cause of morbidity and mortality worldwide, including among adults with hypertension in China. As a medical professor, it is important to critically analyze and evaluate the efficacy of different therapeutic approaches. This report aims to provide an evidence-based analysis of the efficacy of folic acid therapy in the primary prevention of stroke among adults with hypertension in China.

Folic acid, a water-soluble B-vitamin, plays a crucial role in various physiological processes, including homocysteine metabolism, DNA synthesis, and neural tube development. Previous studies have suggested that folic acid supplementation may have potential benefits in reducing the risk of stroke, particularly in populations with hypertension.

Several randomized controlled trials (RCTs) have been conducted to evaluate the efficacy of folic acid therapy in stroke prevention among adults with hypertension in China. One notable study is the China Stroke Primary Prevention Trial (CSPPT), which aimed to determine whether daily folic acid supplementation combined with enalapril, an antihypertensive medication, could reduce the risk of first stroke among individuals with hypertension.

The CSPPT recruited a large sample size of over 20,000 participants and had a follow-up period of 4.5 years. The results of this trial demonstrated significant positive outcomes. Folic acid therapy combined with enalapril was associated with a 21% reduction in the risk of first stroke compared to enalapril alone. Furthermore, subgroup analysis revealed that the beneficial effect of folic acid therapy was more prominent among individuals with lower baseline plasma folate levels.

These findings provide strong evidence supporting the efficacy of folic acid therapy as a primary prevention strategy for stroke among adults with hypertension in China. Folic acid supplementation, when combined with antihypertensive medication, significantly reduces the risk of stroke. However, it is important to note that this study was conducted in a specific population and further research is needed to validate these results in diverse populations.

In conclusion, based on the findings of the China Stroke Primary Prevention Trial (CSPPT), folic acid therapy has demonstrated efficacy in the primary prevention of stroke among adults with hypertension in China. The combination of folic acid supplementation and antihypertensive medication significantly reduces the risk of first stroke. As medical professionals, it is essential to consider these findings when designing treatment strategies for the prevention of stroke in this population. Ongoing research and further clinical trials are necessary to confirm and broaden the applicability of these findings to other populations.

Share This Post

Email
WhatsApp
Facebook
Twitter
LinkedIn
Pinterest
Reddit

Order a Similar Paper and get 15% Discount on your First Order

Related Questions

The construct of cognitive dissonance is based on the notion

 The construct of cognitive dissonance is based on the notion that we will sometimes behave in ways that we don’t like or that clash with certain views we hold of ourselves. For example, we might say or do things (often based on emotion) that we later regret because it does

Review the Capital Gains and Losses information in the Tax

  Review the Capital Gains and Losses information in the Tax Guide 2020 Publication 17 [PDF] located on the IRS website. Analyze the current IRS rules related to capital gains and losses on the sale of real property. Based on your analysis, take a position as to whether you believe the

Topic Interview of Middle Aged Adult and Analysis

Interview Questions must include a rationale (theoretical support from developmental psychology) in order to qualify for full extra credit points. This will help you when you write your final report!Interview an adult who is middle aged or older using the approved interview questions you have developed. Make sure that the

At the State Employment Service, a number of employment counselors

 At the State Employment Service, a number of employment counselors were hired together during a special recruiting effort 12 years ago. They formed a cohort, went through training together, and received graduate hours in vocational counseling together. About a year ago, Jane Midland, the first member of the cohort to

Not only do children and adults have different presentations for

   Not only do children and adults have different presentations for ADHD, but males and females may also have vastly different clinical presentations. Different people may also respond to medication therapies differently. For example, some ADHD medications may cause children to experience stomach pain, while others can be highly addictive

A baccalaureate nurse understands, relates, and values the fundamental elements of research, process, and designs as a foundation for an evidence-based practice (AACN, 2008; QSEN, 2018). Purpose:   Th Nursing Assignment Help

A baccalaureate nurse understands, relates, and values the fundamental elements of research, process, and designs as a foundation for an evidence-based practice (AACN, 2008; QSEN, 2018). Purpose:   This assignment provides a learning activity for students to demonstrate understanding of quantitative and qualitative research, the purpose and importance of designs,

TOPIC: ONLINE HIGH SCHOOL, please review the following instruction and

 TOPIC: ONLINE HIGH SCHOOL, please review the following instruction and need to write a paper on Online High School. for a sample document please look for the attached document.  Review the rubric to make sure you understand the criteria for earning your grade. Construct a proposal to JGJ Inc. of

Instructions Include an explanation as to how Walden’s vision, mission,

 Instructions  Include an explanation as to how Walden’s vision, mission, goals, and social change initiatives relate to your professional and academic goals and to your becoming a scholar-practitioner. Also include an explanation for how the Walden MSN Program Outcomes and perspectives relate to your professional and academic goals and to

Why was Beethoven’s music considered transitional to a new artistic

Critical Thinking Essay #2 Please answer ONE of the following questions in an 600-850 words. Please write an essay in MLA style with an Introduction, Body, and Conclusion. Please cite all ideas which are not your own with supporting research. Plan to consult sources other than your textbook. 1. Why

Prepare a Microsoft® PowerPoint® presentation of no fewer than 12

  Prepare a Microsoft® PowerPoint® presentation of no fewer than 12 and no more than 15 slides with speaker notes, and 3–4 bulleted points per slide, summarizing either: A. An improvement to an existing product or service you have envisioned in the role of a product specialist at a company.

Nursing informatics knowledge, skills, and competencies are so pervasive in

Nursing informatics knowledge, skills, and competencies are so pervasive in the modern technology-rich healthcare environment it is difficult to imagine one without the other. This course provided foundational and introductory knowledge regarding informatics with an emphasis on developing an understanding of concepts of nursing informatics (NI) and becoming knowledgeable about the

M04 Discussion: Should You Eat Every Day? 6767 unread replies.6767

M04 Discussion: Should You Eat Every Day? 6767 unread replies.6767 replies. In this module you learned about cellular respiration which breaks down the food you eat to create energy for your cells (ATP).  The latest from the National Health and Nutrition Examination Survey (posted by the CDC) put the rate

1- Where Does Walmart Supply Chain start? What Trigger Walmart

   1- Where Does Walmart Supply Chain start? What Trigger Walmart retail link system to ship goods to local Walmart stores? 2- Why is detailed knowledge of consumer purchase at each store important to Walmart success? 3- Why can’t other large retailers easily duplicate Walmart retail link? 4- Why does