Read pages 1-5 of the case study, “Statins Stat!” (see

 

Read pages 1-5 of the case study, “Statins Stat!” (see attached pdf below), and answer the following questions.

1.       Why are high density lipoproteins (HDLs) considered the “good cholesterol”? In your answer explain specifically what HDLs do that cause it to be considered the “good cholesterol”.

2.       Why are low density lipoproteins (LDLs) considered the “bad cholesterol”? In your answer explain specifically what LDLs do that cause it to be considered the “bad cholesterol”.

3.       What is the role of the phospholipid monolayer at the outer surface of lipoprotein particles? (Question 1 of case study)

4.       Why are cholesterol, cholesteryl esters, and triglycerides preferentially contained inside lipoprotein particles? (Question 2 of case study)

5.       What are the two sources of cholesterol in the human body?

6.       What is a “committed step” in a biochemical pathway? (Question 3 of case study)

7.       Looking at Figure 4 of case study (the reaction pathway from acetyl-CoA), which enzyme is likely to be the target of the statin mevastatin? (Question 6 of case study)

8.       What are four (4) ways that HDL levels can be increased in the body?

9.       What type of inhibitor (non-competitive OR competitive) are statins with respect to HMG-CoA reductase enzyme activity? Explain why.

10.    How were cholesterol-lowering statin drugs first discovered?

 You will earn 10 pts for correctly answering each question (total points earned is 100).  You may use the Internet and/or your textbook to assist you, but please DO NOT copy your answers directly from the Internet or textbook. 

Share This Post

Email
WhatsApp
Facebook
Twitter
LinkedIn
Pinterest
Reddit

Order a Similar Paper and get 15% Discount on your First Order

Related Questions

Discuss (George Ayyitey (1945-) the Ghanaian economist

Minimum 1,200-word (approx. 5 page) Paper on Macroeconomist of interest to the student It must be about:(George Ayyitey (1945-) – Ghanaian economist (Macro): “Africa is poor because she is not free”) an Economist most of whose work was in Macroeconomics, who refers to one or more principles discussed in this

Give context as to why the issue is a problem.

Give context as to why the issue is a problem. What is the overall citizen view of the issue? What has the state and local government done to address the issue? How does the state response fit with the federal response?  Is the state acting because the federal government isn’t? 

Take Care of Your Heart Health Poster Nursing Assignment Help

  Expert Solution Preview Introduction: As a medical professor, my primary responsibility is to design and conduct lectures, evaluate student performance, and provide feedback through examinations and assignments for medical college students. With a focus on fostering a comprehensive understanding of medical concepts, I aim to equip students with the

Program Portfolio (Capstone) Project – Course MAN 4162: Create a

  Program Portfolio (Capstone) Project – Course MAN 4162:  Create a customer service policy for your business of choice. Address potential consumers needs in the business environment. Include your business client structure, and motivational factors for retaining customers.  Provide research examples to support the development of your Program Portfolio Project

“Ongka’s Big Moka”

We watched “Ongka’s Big Moka” in class, about a leader in Papua New Guinea who was attempting to organize a big feast for a neighboring society. The film is an excellent example of the “Big Man” system. How did Big Men acquire power? (1 point) What sort of powers did

Initial Post To get started, review the Nurse Practitioner Interactive

  Initial Post To get started, review the Nurse Practitioner Interactive Map. In your initial post, please identify the prescriptive authority regulations in the state where you are going to practice. Are there any restrictions, supervision, or collaboration required from a physician? If so, please explain. If you will be

Assignment Content Refer to the information gathered in your Week

  Assignment Content Refer to the information gathered in your Week Three Individual Assignment. Write a 1,750- to 2,100-word comparative analysis of three potential strategies to address the policy problem. In the comparative analysis, address the following for each proposed strategy: The strengths and weaknesses The potential internal and external

The film of environmental issue-“Climate of Doubt”

Watching an environmental film that is called “Climate of Doubt” from Kanopy. https://miamioh.kanopy.com/video/climate-doubt For Page1, paraphrase what the movie presented (Paragraph 1) and your opinion of the film’s presentation of the issue (Paragraph 2). Read TWO separate professional reviews of the film, discuss what each review presented and your opinion

This journal exercise is a free writing assignment. There is

This journal exercise is a free writing assignment. There is no special formatting required. You are allowed to use informal citations, such as hyperlinks. The point of the exercise is to demonstrate your ability to critically think about this week’s lessons. In a single-spaced journal entry of at least 500

What personal strengths do you have that would make you

  What personal strengths do you have that would make you an effective nurse leader? What potential gaps might you need to address to improve your ability to be an effective nurse leader? As a future DNP-prepared nurse, you will be called upon as a leader in your field, a

Finished Financial Paper needs to be reworked DRAFTED to fit

Finished Financial Paper needs to be reworked DRAFTED to fit Professor Template provided.   is written just need calculation ratios from  two below only these ratios ARE REQUIRED BUT ALL MUST BE COMPLETED ACCORDING TO  2 PRPOVIDED This needs to be exact do not take if its not correct I

Assignment – Week 7 Project Which of the topics discussed

  Assignment – Week 7 Project Which of the topics discussed this term did you find most interesting?  Topics are:  Mobile User Interface Design, Mobile Websites Why was the topic interesting? Do you think you will build mobile apps in the future? What is the most complicated aspect of building

SEU Health & Medical Parametric Statistical Testing Discussion Nursing Assignment Help

   Expert Solution Preview Introduction: In the field of medical education, as a medical professor, my primary responsibility is to create comprehensive assignments and examinations for college students in order to assess their knowledge and skills in medicine. Additionally, I develop and conduct lectures to provide students with vital information

In 1976, the mutilated body of Anna Mae Aquash, an

  In 1976, the mutilated body of Anna  Mae Aquash,  an American Indian Activist,  was found on a South Dakota Ranch.  It will take more than 25 years before her killer will be discovered.  Anna Mae’s murder will make national news because of her involvement in the Indian Civil Rights

(At least) One slide for each topic below. Reference is

(At least) One slide for each topic below. Reference is suggested below. You can use additional references if needed.  No images. No bullets. Need more description.  Topics: 1. What are the different tools used in optimizing web pages? How are they designed? Reference: Terrance, A. R., Shrivastava, S., Kumari, A.,

please provide at least one example of a reform that

please provide at least one example of a reform that could be enacted to help prevent wrongful convictions? Elaborate. Could there be an unintended consequences of this reform? Again, please elaborate. Next, what is the “Blackstone ratio” — please discuss this using your own words. Do you feel this is

Reply to: When designing an experimental study, a researcher must

Reply to:   When designing an experimental study, a researcher must decide between utilizing a between-subjects design or a within-subjects design. The main difference between the two is that a within-subjects design involves the use of the same subjects participating within each level of treatment condition, while in between subject